6,859 research outputs found

    Stochastics theory of log-periodic patterns

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    We introduce an analytical model based on birth-death clustering processes to help understanding the empirical log-periodic corrections to power-law scaling and the finite-time singularity as reported in several domains including rupture, earthquakes, world population and financial systems. In our stochastics theory log-periodicities are a consequence of transient clusters induced by an entropy-like term that may reflect the amount of cooperative information carried by the state of a large system of different species. The clustering completion rates for the system are assumed to be given by a simple linear death process. The singularity at t_{o} is derived in terms of birth-death clustering coefficients.Comment: LaTeX, 1 ps figure - To appear J. Phys. A: Math & Ge

    PI3K in T Cell Adhesion and Trafficking.

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    PI3K signalling is required for activation, differentiation, and trafficking of T cells. PI3Kδ, the dominant PI3K isoform in T cells, has been extensively characterised using PI3Kδ mutant mouse models and PI3K inhibitors. Furthermore, characterisation of patients with Activated PI3K Delta Syndrome (APDS) and mouse models with hyperactive PI3Kδ have shed light on how increased PI3Kδ activity affects T cell functions. An important function of PI3Kδ is that it acts downstream of TCR stimulation to activate the major T cell integrin, LFA-1, which controls transendothelial migration of T cells as well as their interaction with antigen-presenting cells. PI3Kδ also suppresses the cell surface expression of CD62L and CCR7 which controls the migration of T cells across high endothelial venules in the lymph nodes and S1PR1 which controls lymph node egress. Therefore, PI3Kδ can control both entry and exit of T cells from lymph nodes as well as the recruitment to and retention of T cells within inflamed tissues. This review will focus on the regulation of adhesion receptors by PI3Kδ and how this contributes to T cell trafficking and localisation. These findings are relevant for our understanding of how PI3Kδ inhibitors may affect T cell redistribution and function

    Log-periodic route to fractal functions

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    Log-periodic oscillations have been found to decorate the usual power law behavior found to describe the approach to a critical point, when the continuous scale-invariance symmetry is partially broken into a discrete-scale invariance (DSI) symmetry. We classify the `Weierstrass-type'' solutions of the renormalization group equation F(x)= g(x)+(1/m)F(g x) into two classes characterized by the amplitudes A(n) of the power law series expansion. These two classes are separated by a novel ``critical'' point. Growth processes (DLA), rupture, earthquake and financial crashes seem to be characterized by oscillatory or bounded regular microscopic functions g(x) that lead to a slow power law decay of A(n), giving strong log-periodic amplitudes. In contrast, the regular function g(x) of statistical physics models with ``ferromagnetic''-type interactions at equibrium involves unbound logarithms of polynomials of the control variable that lead to a fast exponential decay of A(n) giving weak log-periodic amplitudes and smoothed observables. These two classes of behavior can be traced back to the existence or abscence of ``antiferromagnetic'' or ``dipolar''-type interactions which, when present, make the Green functions non-monotonous oscillatory and favor spatial modulated patterns.Comment: Latex document of 29 pages + 20 ps figures, addition of a new demonstration of the source of strong log-periodicity and of a justification of the general offered classification, update of reference lis

    Buckling instability in type-II superconductors with strong pinning

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    We predict a novel buckling instability in the critical state of thin type-II superconductors with strong pinning. This elastic instability appears in high perpendicular magnetic fields and may cause an almost periodic series of flux jumps visible in the magnetization curve. As an illustration we apply the obtained criteria to a long rectangular strip.Comment: Submitted to Phys. Rev. Let

    Weak Measurements with Arbitrary Pointer States

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    The exact conditions on valid pointer states for weak measurements are derived. It is demonstrated that weak measurements can be performed with any pointer state with vanishing probability current density. This condition is found both for weak measurements of noncommuting observables and for cc-number observables. In addition, the interaction between pointer and object must be sufficiently weak. There is no restriction on the purity of the pointer state. For example, a thermal pointer state is fully valid.Comment: 4 page

    Anisotropic thermal expansion and magnetostriction of YNi2_2B2_2C single crystals

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    We present results of anisotropic thermal expansion and low temperature magnetostriction measurements on YNi2_2B2_2C single crystals grown by high temperature flux and floating zone techniques. Quantum oscillations of magnetostriction were observed at low temperatures for H∥cH \| c starting at fields significantly below Hc2H_{c2} (H<0.7Hc2H < 0.7 H_{c2}). Large irreversible, longitudinal magnetostriction was seen in both, in-plane and along the c-axis, directions of the applied magnetic field in the intermediate superconducting state. Anisotropic uniaxial pressure dependencies of TcT_c were evaluated using results of zero field, thermal expansion measurements

    Real time magneto-optical imaging of vortices in superconductors

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    We demonstrate here real-time imaging of individual vortices in a NbSe2 single crystal using polarized light microscopy. A new high-sensitivity magneto-optical (MO) imaging system enables observation of the static vortex lattice as well as single vortex motion at low flux densities.Comment: 3 pages, 1 figur
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